Bio-informatics and Computational biology

Genome browser


  • 說明包含 Ensembl, Havana and UCSC 等基因體搜尋工具的理論或技術。

BLAST (Basic Local Alignment Search Tool)


  • BLAST(Basic Local Alignment Search Tool) is analysis tools/suits of similarity between sequences with nucleotide or protein databases.

Multiple sequence alignment


  • 多序列對準對於基因體、蛋白質體皆為基本概念,透過比對基因或胺基酸序列作為功能性等分析依據。

Entrez


  • The query system to NCBI databases, known as Entrez.

Pattern Recognition


  • 遺傳分子紀錄著生物體的結構 (genotype),在遇到不同的環境下控制生物體運行的法則 (phenotype)。

Molecular Structure


  • The protein conformation determines the function of the protein, however the key to the conformation change is the molecular structure transformation to environment changing.

Next Generation Sequencing (NGS)


  • 次世代定序核心技術為一次打散多組相同的基因體並分別定序後,透過序列比對與重組而找出基因體完整序列。

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